Mincle Agonist: TDM [Cord Factor]
The mycobacterial glycolipid trehalose-6,6’-dimycolate (TDM), also named Cord Factor (CF), is an important regulator of immune responses during Mycobacterium tuberculosis (Mtb) infections. Macrophages recognize TDM through the Mincle receptor and initiate TDM-induced inflammatory responses, leading to lung granuloma formation. controlled use of its cell wall activates macrophages in ways that can be harnessed for therapy. For example, M. bovis Bacille Calmette-Guérin (BCG) is one of the most widely used antitumor adjuvant therapies in humans.
Available from stock for immediate delivery.