Featured products

  • Retinoic Acid powered by LipodisqTM Sterile Solution Cat. No. #IAX-700-109

    Retinoic Acid powered by LipodisqTM Sterile Solution Cat. No. #IAX-700-109

    £165.00

    • Vitamin A is a fat-soluble micronutrient necessary for the growth of healthy skin and hair. However, both too little and too much vitamin A has deleterious effects. All-transretinoic acid (ATRA) and retinal are the main active metabolites of vitamin A. Retinoic acid dose-dependently regulates hair follicle stem cells, influencing the functioning of the hair cycle, wound healing, and melanocyte stem cells. Retinoic acid also influences melanocyte differentiation and proliferation in a dose-dependent and temporal manner. Levels of retinoids decline when exposed to ultraviolet irradiation in the skin.

    • All-trans-retinoic acid (ATRA) is effective for preventing cancer and treating skin diseases and acute promyelocytic leukaemia (APL). These pharmacological effects of ATRA are mainly mediated by retinoid X receptors (RXRs) and retinoic acid receptors (RARs). These included two families of receptors, the RAR isotypes (a,b, and g) along with three RXR isotypes (a,b, and g), which bind as RXR/RAR heterodimers to cis-acting response elements of RA target genes to generate a high degree of complexity. • Retinoic acid is used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus, impetigo, vitiligo, lichen psoriasis, the face of pityriasis alba.

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  • DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC) Cat. No. #IAX-700-400

    DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) (14:0 PC) Cat. No. #IAX-700-400

    From: £42.00

    • A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecular annulus.

    • LipodisqTM polymers are available as 4 defined structures (1:1, 2:1, 3:1 and 4:1 Styrene to Maleic Acid (SMA) rations) each individually operational within a selected pH range for optimal working conditions.

    • Components are batch-tested for LipodisqTM formation using buffer systems available, which are tested for nano-formulated drug analysis by Dynamic Light Scattering (DLS). These buffer solutions are endotoxin-tested and sterile.

    • LipodisqTM formation is highly efficient and nanodiscs show a good safety profile and are suitable for in vitro and in vivo (in experimental animals) investigations.

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  • Lipodisq™ Styrene:Maleic Acid Copolymer 1:1 [SMA-100] Cat. No. #IAX-700-201

    Lipodisq™ Styrene:Maleic Acid Copolymer 1:1 [SMA-100] Cat. No. #IAX-700-201

    £95.00

    • A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecular annulus.

    • LipodisqTM polymers are available as 4 defined structures (1:1, 2:1, 3:1 and 4:1 Styrene to Maleic Acid (SMA) rations) each individually operational within a selected pH range for optimal working conditions.

    • Components are batch-tested for LipodisqTM formation using buffer systems available, which are tested for nano-formulated drug analysis by Dynamic Light Scattering (DLS). These buffer solutions are endotoxin-tested and sterile.

    • LipodisqTM formation is highly efficient and nanodiscs show a good safety profile and are suitable for in vitro and in vivo (in experimental animals) investigations.

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  • Lipodisq™ Styrene:Maleic Acid Copolymer 2:1 [SMA-200] Cat. No. #IAX-700-202

    Lipodisq™ Styrene:Maleic Acid Copolymer 2:1 [SMA-200] Cat. No. #IAX-700-202

    From: £92.00

    • A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecular annulus.

    • LipodisqTM polymers are available as 4 defined structures (1:1, 2:1, 3:1 and 4:1 Styrene to Maleic Acid (SMA) rations) each individually operational within a selected pH range for optimal working conditions. • Components are batch-tested for LipodisqTM formation using buffer systems available, which are tested for nano-formulated drug analysis by Dynamic Light Scattering (DLS). These buffer solutions are endotoxin-tested and sterile.

    • LipodisqTM formation is highly efficient and nanodiscs show a good safety profile and are suitable for in vitro and in vivo (in expermental animals) investigations.

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  • Lipodisq™ Styrene:Maleic Acid Copolymer 3:1 [SMA-300] Cat. No. #IAX-700-203

    Lipodisq™ Styrene:Maleic Acid Copolymer 3:1 [SMA-300] Cat. No. #IAX-700-203

    From: £92.00

    • A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecular annulus.

    • LipodisqTM polymers are available as 4 defined structures (1:1, 2:1, 3:1 and 4:1 Styrene to Maleic Acid (SMA) rations) each individually operational within a selected pH range for optimal working conditions. • Components are batch-tested for LipodisqTM formation using buffer systems available, which are tested for nano-formulated drug analysis by Dynamic Light Scattering (DLS). These buffer solutions are endotoxin-tested and sterile.

    • LipodisqTM formation is highly efficient and nanodiscs show a good safety profile and are suitable for in vitro and in vivo (in expermental animals) investigations.

    Add to Cart
  • Lipodisq™ Styrene:Maleic Acid Copolymer 4:1 [SMA-400] Cat. No. #IAX-700-204

    Lipodisq™ Styrene:Maleic Acid Copolymer 4:1 [SMA-400] Cat. No. #IAX-700-204

    £92.00

    • A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecular annulus.

    • LipodisqTM polymers are available as 4 defined structures (1:1, 2:1, 3:1 and 4:1 Styrene to Maleic Acid (SMA) rations) each individually operational within a selected pH range for optimal working conditions. • Components are batch-tested for LipodisqTM formation using buffer systems available, which are tested for nano-formulated drug analysis by Dynamic Light Scattering (DLS). These buffer solutions are endotoxin-tested and sterile.

    • LipodisqTM formation is highly efficient and nanodiscs show a good safety profile and are suitable for in vitro and in vivo (in expermental animals) investigations.

    Add to Cart