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Monophosphoryl Lipid A [MPLA] E. coli R515 (Re) TLRpure Sterile Cat. No. #IAX-100-003
£288.00
NEW: Introducing a Selection of APIs nano-formulated in LNP for improved PK/PD: Compounds powered by LipodisqTM
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Potent and TLR4-exclusive ligands, devoid of other TLR stimulating contaminants in a stable, sterile aqueous solution for maximal reproducibility of experiments, especially for pre-clinical use.
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IAXO/FP small molecules as synthetic lipid A analogues and high potency human Toll-like Receptor (TLR) 4 blocking monoclonal antibodies.
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Endotoxin-free Buffers & Solutions (sterile) are important for reproducible and specific endotoxin and endotoxin-free preparations.
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Lipid-nanodisc formulation with solubilised hydrophobic actives in water (sterile) Ready-to-Use
- Polymeric SMA-Lipodisq Lipid nano-particles (SMA-LNP) are useful as drug delivery systems comprising a discoidal phospholipid bilayer membrane stabilised by a chaperone molecule annulus (11-40nm).
- The resulting encapsulated actives are rendered water-soluble and specialised for intra-cellular penetration/delivery via endosomal uptake mechanisms, which allow for improved PK/PD of the API.
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Literature
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